Critical Reasoning: Double-blind Trial

XAT 2019 · VALR · Medium · Critical Reasoning

Read the following paragraph and answer the question that follows:

An accurate measure of drug efficacy would require comparing the response of patients taking it with that of patients taking placebos; the drug effect could then be calculated by subtracting the placebo response from the overall response, much as a deli-counter worker subtracts the weight of the container to determine how much lobster salad you're getting. In the last half of the 1950s, this calculus gave rise to a new way to evaluate drugs: the double-blind, placebo-controlled clinical trial, in which neither patient nor clinician knew who was getting the active drug and who the placebo.

Which of the options is a wrong answer to this Question How does a double-blind ensure a better trial of a new drug?

  1. A.

    It increases the overall response to the drug.

  2. B.

    The patient does not know whether he/she is getting a placebo.

  3. C.

    It reflects the calculus exemplified by the deli-counter episode.

  4. D.

    The clinician cannot pick and choose patients to whom placebos can be administered.

  5. E.

    It gives rise to an unbiased testing of drugs.

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